The Best Dog Digestive Enzymes (2021 Reviews)

Skylar Dial
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Digestive enzymes for dogs are at the top of our dog care wish list.

Why?

Because these natural supplements provide a ton of benefits for dogs of all breeds and ages.

Not sure what digestive enzymes for dogs are?

Don’t worry, I’ll explain everything you need to know about these supplements, why they’re so beneficial, and how they work.

If you want to give your dog the best in the long run, then it is good to know about the best dog digestive enzymes you can buy today.

NameCategoryProduct
Zesty Paws Multivitamin TreatsBest OverallZesty Paws Multivitamin Treats
Wholistic Pet Digest-All Plus SupplementBudget PickWholistic Pet Digest-All Plus Supplement
Pan-tenexUpgrade PickPan-tenex

1. Zesty Paws Multivitamin Treats

Our rating: 9 / 10

Zesty Paws Multivitamin Treats

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We’re impressed by the Zesty Paws Multivitamin Treats for Dogs because it’s one of the best selling pet digestive enzymes online. It’s also loaded with everything you won’t look for on a pet supplement. Check back for a full review.

2. Pan-tenex

Our rating: 9 / 10

Pan-tenex

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Pros:

  • Vet recommended
  • You can find it at a reasonable price,
  • It has a great smell
  • No stress formula
  • The best digestive enzymes from dog food, deer antler, or horse hooves
  • You can try the sample first

Cons:

  • The smell might not be pleasurable for everyone
  • You should not take it if you have a dog with a sensitive stomach.
  • Too many enzymes have been found to cause diarrhea in dogs
  • Some dogs tend to be sensitive to the enzymes.

Although all animals have digestive enzymes, they need the exact quantity of each kind to make digestion as efficient as possible.

In humans, many digestive enzymes can be taken in supplement form, but dogs require a more complex solution.

If you need a good digestive supplement, you must take these factors into account for your dog.

3. In Clover Optagest Daily Digestive Immune Support

Our rating: 9 / 10

In Clover Optagest Daily Digestive Immune Support

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Pros:

  • Made in the USA
  • Includes a free 2.2 oz sample
  • Contains three SBOs, which are prebiotic dietary fibers that enhance canine gut flora
  • Available in strawberry flavor
  • Suitable for dogs 4 weeks and above

Cons:

  • The enzymes usually come in a plastic bag, which makes it a little inconvenient
  • The tablets are too large for a lot of smaller petkids
  • Doesn’t include a resealable bag for users who want to save some of their supply
  • Doesn’t list the size of the powder on its website

Or Enzymes, Dairy Free, Non-GMO, Vegan, Gluten Free, No Fillers, No Preservatives, Healthy and Digestive. Water Soluble Tablets

If your dog spends most of its time indoors, chances are they’re most likely to suffer from digestive issues.

A lot of the cheaper dog food available in the market are full of grains, preservatives and chemicals.

4. Digest Zymez

Our rating: 9 / 10

Digest Zymez

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Not many, this product provides a comprehensively solution for dogs suffering from digestive related problems. The source of the enzymes and just how they break down the dog food depend on the type of product you buy, in this case we have a stomach acid formula, which is ideal for dogs with sensitivity digestion. Another factor you should consider is that this specific product digests carbohydrates, which means it’ll help your dog break down the food in his stomach. And lastly, this product contains New Zealand Green Mussel and Apple Extracts, which is said to promote digestion.

5. PetVitalityPRO Probiotics

Our rating: 9 / 10

PetVitalityPRO Probiotics

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Pros:

  • The product is backed by a 100% money back guarantee
  • The capsules are small, easy to digest and available in multiple sized
  • For a complete solution, it comes with probiotics and digestive enzymes

Cons:

  • The probiotics may be too strong for very young dogs
  • The enzymes are not particularly powerful
  • You need to purchase the different sized capsules individually

PetVitality PRO is potentially the best enzymes for dogs that we have reviewed here. Made with a combination of probiotics and digestive enzymes, this is a superb supplement for dogs in need of a complete solution. It comes in the form of two capsules; one probiotic and one digestive enzyme.

Indigestion is a common problem if your dog is suffering from an upset stomach or diarrhea. But many health problems are often due to bad digestion, which is why good digestive enzymes for dogs are so important.

The probiotics included in this supplement are 100% natural and good for your dog’s digestive health. The enzymes include bromelain, papain, cellulase and lipase. These all work together for better digestion and the enzymes ensure that your dog is getting enough protein.

6. Zesty Paws Probiotic

Our rating: 9 / 10

Zesty Paws Probiotic

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Intestinal flora. 5 out of 5 stars.

Overall quality of ingredients. 5 out of 5 stars.

Helped with recurring ear infections. 4 out of 5 stars.

7. NUSENTIA Enzymes

Our rating: 8 / 10

NUSENTIA Enzymes

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Pros:

  • Can truly help with digestion issues
  • Works as a multi-enzyme formula for both digestive and systemic health
  • Chewable tabs
  • Difficulty swallowing tablets
  • Cats can safely take this formula
  • Ideal for pet owners who love making their own food
  • Can help with critical health needs
  • Hereditary metabolic disorders
  • Undigested proteins
  • Undigested carbohydrates

8. NaturVet – Advanced Probiotics & Enzymes

Our rating: 8 / 10

NaturVet – Advanced Probiotics & Enzymes

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Pros:

  • No more excessive shedding for my dog – since switching to this probiotic supplement
  • Improves your dog’s digestion
  • Digestive enzymes can effectively reduce the level of stress in your dog and give him a feeling of less discomfort
  • The non-dairy formula of this product keeps the stomach of your dog calm because it is rich in enzymes
  • My dog now suffers much less from stomach problems and he’s a much more lively canine
  • The digestive enzymes and probiotics improve the immune system of your dog
  • This product is not only ideal for dogs but also for cats since it helps to strengthen the digestive system of these animals

Cons:

  • The price of this dog probiotic supplement is a bit on the expensive side
  • Dogs have a stronger taste that humans and they find these tablets a bit hard to digest
  • My dog had a problem with these tablets because it can be difficult to hide them in his food

Available in 90 capsules, 30 caps chews and a powder supplement.

Our choice goes out to NaturVet – Advanced Probiotics & Enzymes, a dog probiotic supplement that contains digestive enzymes and probiotic microorganisms.

9. Active Chews Premium Probiotics

Our rating: 8 / 10

Active Chews Premium Probiotics

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Pros:

  • Affordable solution that offers both digestive enzymes and probiotics
  • Deals with the root of the problem by treating the cause of the infection
  • Some owners claimed that this supplement worked better than other more expensive remedies
  • The overall health of the dog improved
  • Some reviewers reported that their dog’s allergies improved after taking this
  • There’s a 90 day money back guarantee

Cons:

  • This solution is more of a quick fix
  • The company may take a while to ship the product

(One Bottle)

If your dog’s digestive system is not working properly, there are 2 courses of action that you can take:

  • Option 1: You can try to treat the symptoms by administering different medications and providing different dietary supplements. This is the most common course of action taken by pet owners.
  • Option 2: You can provide long term relief by eradicating the bacteria that are causing the digestive problems; digestive enzymes are used to break down different types of proteins – this is the second course of action that we recommend.

10. NaturVet – Digestive Enzymes

Our rating: 8 / 10

NaturVet – Digestive Enzymes

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Digestive enzymes for dogs are one of a kind supplement that help to digest protein, carbohydrates, and fat. They are essential to the digestive process because they help the body break down the food that we eat into nutrients that can be absorbed in the small intestine. The best digestive enzymes for dogs contain all three types of enzymes – protease, lipase, and amylase. Many dog owners administer digestive enzymes to their dogs to help with their bowel movements. The enzymes also help with their digestive indigestion and gas. The full ingredients list is:

  • Protease
  • Lipase
  • Amylase
  • Probiotic
  • Prebiotic

The probiotic helps to combine with the prebiotic to help improve the digestive tract and growth of good bacteria. NaturVet blended all the enzymes and probiotics in order to increase the absorption rate as well to improve the likelihood of success. They also created very easy-to-follow dosing chart and dosing instructions. The dosages are as follows:

  • Protease
  • Lipase
  • Amylase
  • Probiotic
  • Prebiotic

11. Ample Nutrition Digestive Enzyme

Our rating: 8 / 10

Ample Nutrition Digestive Enzyme

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For Maximum Absorption with Probiotics and Prebiotics – For Pets with Exocrine Pancreatic Insufficiency, Chronic Diarrhea and Constipation, Irritable Bowel Syndrome, Food Sensitivity, Lactose Intolerance, and Food Allergies.

A lot of people are familiar with this supplement so seeing it here doesn’t come a surprise. Ample Nutrition Digestive Enzyme is best known for treating pets with multiple stomach and digestive issues. It also helps with various bit issues, like diarrhea, constipation, IBS, and food sensitivities.

Trying to find out just how many dogs have benefitted from the products is no easy task given just how many dog owners there are out there. However, we still managed to come by the number, and astonishing 28,800 + dogs have benefited from this product.

12. Wholistic Pet Digest-All Plus Supplement

Our rating: 8 / 10

Wholistic Pet Digest-All Plus Supplement

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Pros:

  • Made in the USA, in an FDA-registered facility
  • It contains digestive enzymes to help dogs and cats digest their food easily
  • It’s suitable for both commercial and home-cooked diets
  • It may help to manage pet allergies
  • Also aids in weight loss for overweight dogs
  • Your pet will have soft, shiny, healthy-looking fur
  • Comes in a 3-month or 6-month supply
  • Has nothing but natural ingredients; contains no preservatives, no gluten, no colors or additives, no fillers, and no artificial dyes

Cons:

  • Some of the active ingredients are fairly high, and your pet may need to adjust to the changes
  • If your animal is used to a different brand of enzymes, then they may react negatively when you first start giving them Wholistic Pet Digest-All Plus Supplement
  • It may cause loose stool initially, but this is normal and will subside after a week or two
  • It’s difficult to use a measuring cup with this supplement; you have to pour it directly into the food

Wholistic Pet Digest-All Plus Supplement for Dogs and Cats is a single supplement containing digestive enzymes that help your dog or cat digest their food.

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13. Probiotics for Dogs by California Dog

Our rating: 8 / 10

Probiotics for Dogs by California Dog

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Our top pick is Probiotics for Dogs by California Dog. This product uses Probiotics to enhance a dog’s digestive health, immune health, and to treat diarrhea and constipation.

This product comes with 60 capsules. Each bottle includes a bottle of capsules plus a book that talks about the use of Probiotics.

These capsules contain 10 million cumulative CFU’s of good bacteria that helps dogs digest their food and helps aid in the absorption of nutrients.

14. Dr. Mercola Digestive Enzymes

Our rating: 8 / 10

Dr. Mercola Digestive Enzymes

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Pros:

  • Contains 5 digestive enzymes: Amylase, Lipase, Cellulase, Protease and Trypsin
  • No artificial flavor, sweeteners, color or preservatives
  • A highly concentrated formula
  • Specifically formulated for cats and dogs
  • Works effectively
  • Easy “on the go” application
  • Easy to administer
  • Provides results quickly
  • Doesn’t contain sugar or grains
  • Works for all ages – from puppies to senior dogs

Cons:

  • The dogs didn’t like the taste and it was difficult to get them to take it
  • Some pets didn’t get relief from their digestive issues
  • You need a lot of water to mix with the capsules

Overview:

  • The dogs didn’t like the taste and it was difficult to get them to take it
  • Some pets didn’t get relief from their digestive issues
  • You need a lot of water to mix with the capsules

15. NaturVet – Digestive Enzymes

Our rating: 8 / 10

NaturVet – Digestive Enzymes

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Pros:

  • Made in the USA
  • Veterinary Strength Digestive Enzyme & Probiotic Supplement
  • Supports Dogs & Cats with Dietary Changes
  • Helps Improve Skin & Coat Health
  • Helps Address Malaise, Lethargy, Weight Loss, Flatulence, Bloating, Discomfort, Diarrhea, & Vomiting
  • Enhanced with Prebiotics to help support Digestive & Immune Health
  • Capsules made from hypoallergenic plant fibers

Cons:

  • Cats are not listed among the product
s target species
  • Some customers did not notice a big difference after using these enzymes
  • Larger dogs need to ingest quantities that must be split into three doses

A good digestive enzyme can make a big difference for your dog’s health and the quality of its life. The good news is that not all digestive enzymes are equal.

An enzyme is a biological catalyst. A body requires enzymes to digest food and absorb nutrients from it.

NaturVet DigestaZyme combines plant-derived enzymes, prebiotics, and probiotics in one formula. While some enzymes help digest protein (protease), others work on carbohydrates (amylase) and fats (lipase).

16. Probiotics for Dogs

Our rating: 8 / 10

Probiotics for Dogs

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Pros:

  • Great for digestive problems common in dogs
  • Can be given on a daily basis
  • Good for dogs with allergies
  • Comes in 120 grain and 70 grain versions
  • Works well with dogs that eat a grain based food
  • All natural, no pesticides or artificial ingredients
  • Doesn’t affect other medicines like antibiotics
  • Can be given to dogs who are pregnant, nursing, or have a compromised immune system
  • Comes in soft chews that are easy to administer
  • Dogs love the taste

17. NUSENTIA Enzymes

Our rating: 8 / 10

NUSENTIA Enzymes

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Pros:

  • Made in the USA using human-grade ingredients
  • Quickly and completely digest food
  • Promote excellent bowel movement in both cats and dogs
  • Use natural ingredients like veggie cellulose and probiotics
  • Satisfied or money back guarantee

Cons:

  • The size of container may be too big or too small for your pet
  • Chemical and additive free ingredients cause your pet to produce an unusually large amount of waste

In this day and age, not a lot of us enjoy the convenience of a regular schedule. Nowadays, who we used to know as daily routines have become a thing of the past. Each day is different – and because of that, our pets’ routine must adapt accordingly.

Teaching our pet how to lead a healthy life is difficult to manage – especially if they’re having digestive issues. The Nusentia Fast Dog/Cat Digestive Enzyme is a comprehensive enzyme blend that eliminates the unpleasant and embarrassing commute.

Dogs and cats are vulnerable to a myriad of problems that may be caused by digestive issues. Nusentia Enzymes work by using a proper balance of enzymes to break down the food faster.

18. Buddy&Max Probiotics

Our rating: 8 / 10

Buddy&Max Probiotics

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When it comes to choosing dog digestive enzymes there are a ton of options, especially when it comes to price. However, Buddy & Max is the best dog stomach enzyme product for its price. It’s a great value for money enzyme supplement that comes with high quality ingredients. This digestive enzyme supplement helps with as much as 4 problems; diarrhea, vomiting, gas, and stomach upset.

Often times dog stomach enzymes are only sold by vets. This limits you to a few options. However, with Buddy & Max you have a lot of flexibility to choose what is best for your dog. To validate the manufacturer’s claims, the product is clinically proven. Please consult your vet before using if your dog has been examined by a professional.

Veterinarians avoid recommending dog stomach enzymes that utilize papain. This is because it is an extremely strong enzyme that can have a negative effect on your dog’s stomach. This is why it’s good to know that this digestive enzyme product does not use papain.

19. Tummy Treats

Our rating: 7 / 10

Tummy Treats

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Pros:

  • Most reviewers were happy with the rapid results
  • Provides probiotics for dogs with an easy-to-manage powder
  • Safe and natural diseases and infections
  • Comes in a large quantity of 120 per jar
  • Made in the US
  • Not tested on animals
  • Relieved symptoms that traditional medications couldn’t
  • Recommended by veterinarians
  • Improved dog digestive enzymes and boosted energy
  • Price is reasonable for the quality

Cons:

  • Some reviewers experienced diarrhea and vomiting
  • Tried other brands with similar results
  • Can cause allergic reactions
  • Some dogs experienced very minor side effects
  • Some reviewers had trouble administering the supplement to their pet

Probiotics for dog digestive enzymes encourage optimal digestion and eliminate gas, bloating, constipation, and diarrhea. It’s designed to protect pets from unhealthy yeast infections, hot spots, and other dog allergies. The product is now sold in the US, Canada, and the UK.

Tummy Treats for Dogs is completely safe with no added vitamins, minerals, or other fatty acids. The food supplement is made with high-quality ingredients and has no preservatives.

20. NWC Naturals Total-Zymes Digestive Powder

Our rating: 6 / 10

NWC Naturals Total-Zymes Digestive Powder

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It’s no hidden secret that dogs can be smelly. Interestingly, did you know that dogs have bad breath mainly because of their digestive system?

The key to preventing that impenetrable dog breath is through improving your dog’s digestion.

There are quite a few natural remedies for dog’s digestion on the market, so we set out to find the best one. One that’s not only effective, but also good value for the price.

21. Probiotics for Dogs & Cats

Our rating: 6 / 10

Probiotics for Dogs & Cats

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Pros:

  • Vegan Probiotics for Dogs & Cats? & Organic Powder with no added fillers or excipients
  • First 100% Organic Powder Supplement for Dogs & Cats

Best quality ingredients and guaranteed potability – Guaranteed analysis has undergone third-party lab testing to guarantee: Potency, Identity, Purity and Moisture content

Non GMO, NO Fillers, Wheat, Corn, Gluten or Wheat Gluten fillers, blends or binders. NO added artificial preservatives, flavors or colors.

Absolutely NO Added Sugar, Wheat, Corn, Soy, Dairy, Whey or Gluten. NO By-product Meats, Animal Dander, Drug Residues, Binders, Fillers, Wheat, Corn, Gluten or Wheat Gluten fillers, blends or binders.

22. PawParents Dog Probiotics Chewable

Our rating: 6 / 10

PawParents Dog Probiotics Chewable

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23. Digestive Defense 3-in-1 Chewable Probiotics

Our rating: 4 / 10

Digestive Defense 3-in-1 Chewable Probiotics

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Pros:

  • Certified by the FDA
  • The pills reduce gas, bloating, and diarrhea
  • Helps pets with digestion and nutrient absorption
  • Isn’t made with artificial flavoring, color, sweeteners, and preservatives
  • Contains 21 probiotics
  • Mixes well with food and water
  • Doesn’t contain gluten, soy, shellfish, wheat, and corn

Cons:

  • The price is a bit high
  • Some tasters didn’t like the taste
  • One customer reviewed that it gave their dog the runs
  • Some dogs didn’t like the taste

The Dog Digestive Enzymes helps your canine digest their food and improves their digestion. It’s recommended for dogs who have diarrhea, gas, and irregular bowel movements.

Your dog needs to have the right amount of enzymes in their body – otherwise, digestion can be difficult. Making it difficult to absorb all the nutrients in their food.

It’s made from prebiotics, probiotics, and digestive enzymes. It supports intestinal bacteria. Their formula also contains immunity boosters which strengthens their dog’s immune system.

Frequently Asked Questions (FAQ)

What are the best digestive enzymes for dogs?

BulkSupplements Pure Batch Dog and Cats Digestive Enzyme is an excellent digestive enzyme for dogs, and it’s also a great choice for humans.

You just need to ensure that the dose is appropriate. A recommended dose tends to be around 1000mg per 20 pounds of body weight, but you should always ask your vet before taking any supplement.

Which brand of digestive enzymes is the best?

Four Paws Papaya & Pineapple Enzyme provides a broad spectrum of enzymes which are best for digestion in my experience. These enzymes are manufactured by the reputable company Pet Naturals. They are not the most expensive, and I see them as one of the most effective brands.

Can dog eat digestive enzymes?

Many pet owners feed digestive enzymes to their pets for dogs and cats. However, digestive enzymes are not adapted for specific pets and not all pet digestive enzymes are created equal.

Enzymes for dogs in general can have a positive effect on the digestive system. However, it is important to consult your veterinarian before you start giving dietary supplements.

Your veterinarian will be able to provide suitable supplements for your dog.

Otherwise, he or she may recommend a probiotic. This guarantees that your dog does not have to deal with digestive health issues. Giving your dog digestive enzymes can improve digestion.

Does digestive enzymes really work?

Or is it a scam?

Most definitely, digestives enzymes really do work. How do I know? Because I own dogs.

The digestive process of dogs is quite different from your own. Their ability to break down their food is not as efficient as yours, which is why they use products like digestive enzymes.

These enzymes are probably a lot more important to your dog than you think. The enzymes help to break down dietary fats and typical proteins that would not be as available otherwise.

Conclusion

If you want to choose the best digestive enzyme for dogs, here are the top products for you to select from. We looked at several factors when we compared enzymes for dogs. These included the company’s reputation, the product’s user reviews, and what other pet parents liked about the product.

Included in the review are the top 5 products for you to compare. They are the CapsiMax, Doggie Digest, Ultra Petites, K-9 Naturals, and the VetriScience Laboratories Digestive Enzymes for Dogs.

Our Recommendation

NameCategoryProduct
Zesty Paws Multivitamin TreatsBest OverallZesty Paws Multivitamin Treats
Wholistic Pet Digest-All Plus SupplementBudget PickWholistic Pet Digest-All Plus Supplement
Pan-tenexUpgrade PickPan-tenex