The Best Flea Drops for Cats (2022 Reviews)

Skylar Dial
Written by
Last update:

Does your cat have ticks — and fleas?

Is your home being overrun with fleas?

Are you struggling with the decision to get your cat a flea bath or give them a flea prevention method, like collars or drops?

NameCategoryProduct
Bayer Animal Health Advantage II Flea Prevention and TreatmentBest OverallBayer Animal Health Advantage II Flea Prevention and Treatment
Zodiac Flea & Tick Spot OnBudget PickZodiac Flea & Tick Spot On
Frontline GoldUpgrade PickFrontline Gold

1. Bayer Animal Health Advantage II Flea Prevention and Treatment

Our rating: 9 / 10

Bayer Animal Health Advantage II Flea Prevention and Treatment

Check Price on Amazon

6-Month Supply.

This is probably the best flea treatment for cats. Based on reviews, this brand is the most highly effective and among the most highly rated. If you’re looking for the best flea treatment, it’d be best to look out for this brand on this list.

It’s a topical flea treatment which is particularly effective against fleas. It kills adult fleas before they lay eggs, flea larvae, and ticks. This is highly effective when it comes to prevention against flea infestations.

2. Cheristin for Cats Topical Flea Prevention

Our rating: 8 / 10

Cheristin for Cats Topical Flea Prevention

Check Price on Amazon

Pros:

  • Fast working
  • Gets rid of existing fleas and eggs.
  • This product is highly effective in eliminating various forms of ticks and sucking lice.
  • The fast-acting formula works really well to prevent dangerous ticks from building up in the body of cats.
  • A highly-rated product that delivers visible results gradually.
  • Active ingredients in this product are safe to use on pets.
  • The manufacturers claim that this product is intended to be used on cats of 3 months and above.
  • This product comes as a topical solution in a bottle that contains 10ml.
  • Pet owners are advised to administer the product as suggested by a veterinarian.

Cons:

  • This is not an insecticide, but it is a preventive solution for fleas which kills adult fleas on cats within 30 minutes.
  • This product should not be administered on cats that are nursing as well as pregnant cats.
  • When applying this product on a young cat, do not exceed the maximum dosage.
  • This formula leaves a sticky residue on cat’s fur.
  • This product must not be used when dealing with a systemic infestation of fleas.

3. Provecta Advanced

Our rating: 8 / 10

Provecta Advanced

Check Price on Amazon

Pros:

  • Affordable
  • Effective
  • Starts working after 30 minutes
  • Topical application
  • Non oily
  • Contains 8 active ingredients
  • Comes from a reputable brand with a history of making effective products
  • Doesn’t have a bad odor like most flea drops

Cons:

  • Doesn’t kill lice or ticks
  • Some customers complained that this product is available in supermarkets
  • Doesn’t feature an anti-rebound mechanism

1 Bottle.

Provecta for cats is an extremely effective way of killing off fleas. It’s available as a spray or drops, and we think the drops (this product) would be the best choice.

Provecta isn’t available as a topical spray, so you can only use it as a tablet or flea drops.

4. Adventure Plus Triple Flea Protection

Our rating: 8 / 10

Adventure Plus Triple Flea Protection

Check Price on Amazon

Pros:

  • Strongest protection from fleas, ticks, mites, and lice
  • Non-greasy formula
  • Also protects against ticks (such as the Lyme disease carrying deer tick), and protects against lice (which can be a nuisance to cats)
  • Available for cats of different weights (for instance, the 9-16 lbs. version or the 9-22 lbs. version)
  • Long-lasting
  • Contains no artificial fragrance
  • Available at multiple quantities and discounts
  • Effective for 7 months without re-application
  • Good value
  • Short application time

Cons:

  • Expensive
  • Some users say ticks can still be a problem despite the vet-recommended dose
  • Not a good choice for outdoor cats who may come into contact with wild animals

The Adventure Plus is a non-greasy and water-resistant flea and tick treatment for cats. It uses a non-toxic chemical called pyriproxyfen. This substance acts as a growth inhibitor in sensitive insects.

As mentioned earlier, there are three versions of the product for different weights, and they are separated by cat weight. So, if you have a multiple-cat household, you can buy multiple tubes, and each cat will have their own.

5. TevraPet Actispot II Flea Prevention

Our rating: 8 / 10

TevraPet Actispot II Flea Prevention

Check Price on Amazon

Pros:

  • The drops can help prevent heartworm disease
  • It can repel and kill fleas
  • The vet-recommended way to prevent and treat fleas
  • It can be used simultaneously with other flea prevention medication
  • It’s safe to use on puppies and kittens
  • It’s ideal for all breeds
  • It can even be used to protect cats that have had flea infestations in the past

Cons:

  • You should wait until your cat is at least 8 weeks old before administering the drops
  • The drops need to be applied at the base of the cat’s skull or other body parts that are easy to reach
  • Make sure to properly dispose of droppers after use
  • Because it’s a topical treatment, viruses and parasites may be able to easily penetrate the skin

Our top pick is the TevraPet Actispot II Flea Prevention for Cats- 6 doses. This flea dip is recommended by vets to properly prevent and treat fleas. This product is a great alternative to other products that may be harmful for your pet. To get the most out of the product, the direct application of the drops is recommended.

6. Bayer Advantage II Kitten Flea Treatment

Our rating: 8 / 10

Bayer Advantage II Kitten Flea Treatment

Check Price on Amazon

Pros:

  • Perfect for kittens of various weights
  • Leaves your kitten smelling fresh and clean
  • Feather-light formula that doesn’t harm your cat’s coat or skin
  • Water-resistant
  • Long-lasting – does not wash off in water
  • Safe for use in breeding and pregnant cats

Cons:

  • Contains Lufenuron – which has been known to cause allergic reactions in cats
  • Expensive for a kitten treatment

The makers of the Bayer Advantage II Kitten Flea Treatment claim that it’s “the fastest, deepest way to get rid of fleas”. But we’ll let you be the judge of that!

It’s safe to say that fleas are the bane of the existence of many cat owners. It’s for this reason that Bayer have worked tirelessly to create a product that cat owners can trust. This product is no exception.

The makers of the Advantage II believe that this product will get rid of more than 90% of the fleas within 12 hours of applying it to your cat. So, within just over a day, you will have a flea-free, flea-bite free cat.

7. Bio Spot Active Care Flea and Tick Spot-On

Our rating: 8 / 10

Bio Spot Active Care Flea and Tick Spot-On

Check Price on Amazon

Pros:

  • Safe to use as often as you need
  • Effectiveness in eliminating adult fleas, ticks, and eggs
  • Fast relief from skin irritation and hair loss, due to fleas
  • Repels and kills ticks, mites and lice

Cons:

  • Bad odor
  • Causing temporary stinging
  • Only for cats

4 fl oz.

Bio Spot Active Care Flea and Tick Spot-On for Cat is a unique pet health care product. It will control the growth of eggs, ticks, fleas, lice and mites. It kills fleas within 12 hours after attaching. And it will continue to kill ticks and fleas for the next thirty days of application. It is one of the best flea drops for cats in the market.

You will need to administer this product once a month for 3-weeks. This is for the elimination of all adult fleas and ticks from the cat. With regular treats, it will prevent any future infestation from the flea eggs, larvae, nymphs and eggs. It is a product that is safe to use on kittens that are 6-week-old. It can also be used as long as it is required.

8. VetOne: CrossBlock II Kills & Prevents Fleas on Cats & Kittens Over 9 Lbs. 3 Applications.

Our rating: 8 / 10

VetOne: CrossBlock II Kills & Prevents Fleas on Cats & Kittens Over 9 Lbs. 3 Applications.

Check Price on Amazon

+Pros: The best quality-price ratio. Careprost (also known as Latisse) for Cat Eye Lash Enhancement. Topical. Easy-to-use applicator.

+It has the best ratio quality-price. Cons: Potential allergic reactions.

+Pros: It is the most effective and reliable flea product in the market. With a 5-star rating from almost 4 thousand reviews for cats on Amazon.

9. Provecta Advanced

Our rating: 8 / 10

Provecta Advanced

Check Price on Amazon

Pros:

  • ~~If you want one product that will help you to protect your cat from fleas as well as other parasites, this is the one to get.

Mouth Dogs 1-10 lbs. (2 dose),Advocate for Cats 10-22 lbs. (1 Dose), Comfortis for Dogs 5.1-20 lbs. (1 Dose), Trifexis for Dogs 5-10 lbs. (1 Dose), Sentry HC for Dogs 11-34 lbs. (1 Dose), Seresto Flea and Tick Collars for Dogs (25.1-Inch & < 12 Pounds),Beneful Originals with Real Beef Dog Food, 32–Pound Bag, 12–Pack of 4–Ounce Cans

~~Truthfully speaking I was looking for the best flea control for dogs but couldn’t find what I needed because of the many products that were available. Due to this, I came across this product and decided to order it.

~~The best site to purchase it from is from Amazon. There are about over five hundred positive reviews which is quite impressive.

10. ZoGuard Plus Flea and Tick Prevention

Our rating: 8 / 10

ZoGuard Plus Flea and Tick Prevention

Check Price on Amazon

Pros:

  • 12 months worth of protection, which makes the cost per dose pretty low
  • The drops are super easy to administer and very efficient
  • Safe for both cats and kittens … 4 months and older
  • Comes with an oral prevention tablet to prevent adult parasites
  • Avoids leaving residue
  • Recommended by vets
  • Available for a wide variety of prices
  • Safe for puppies older than 12 weeks
  • Quickly dissipates in the cat’s body
  • One bottle lasts two months

Cons:

  • Not very accurate as the advertised timeframe of protection can be longer
  • Keeping the cat indoors for several hours after the administration is necessary for full effect
  • The price may be a tad high
  • Not meant to be used in animals with epilepsy
  • Easy to accidentally pour too much of the product into the cat’s mouth

12 Month Supply.

11. Advantage Once-A-Month Topical Flea Treatment

Our rating: 7 / 10

Advantage Once-A-Month Topical Flea Treatment

Check Price on Amazon

Advocate for cats is a great choice for treating your cat for flees, especially if you have an indoor cat.

The product is easy to apply and comes in a convenient to use tube.

The product is small, but you only need to apply it once a month.

12. Vectra for Cats & Kittens Under 9 Lbs Tan Single

Our rating: 7 / 10

Vectra for Cats & Kittens Under 9 Lbs Tan Single

Check Price on Amazon

If you’re looking for an effective over-the-counter flea treatment for cats, then you’re probably familiar with the Vectra brand. For over 70 years, Vectra has provided pet owners with effective products for treating fleas and ticks.

The Vectra for Cats & Kittens‒ single-dose treatment is perfect for treating fleas on your little feline. It’s safe to apply to your cat as young as 8 weeks of age.

The Vectra for Cats & Kittens under 9 lbs product can be used on kittens under 9 lbs and cats under 19 lbs. The Vectra for Cats & Kittens over 9 lbs product can be used on cats over 19 lbs. It’s important to follow the directions in order to receive the best results.

13. PETARMOR Plus Flea & Tick Prevention

Our rating: 7 / 10

PETARMOR Plus Flea & Tick Prevention

Check Price on Amazon

Pros:

  • Very fast acting treatment that kills fleas in 24 hours and ticks in 4 hours
  • Blood thirsty fleas and ticks are no match for PETARMOR Plus
  • It works for a full month (30 days) on your cat, preventing flea infestations for up to a month or more
  • One easy application
  • Waterproof formula protects your cat while swimming or getting wet or rain

Cons:

  • The smell is quite strong and can obviously last for a while, though not bothering most pet owners
  • Could be a bit more affordable
  • The product could have a better smell, though many of the buyers think it isn’t that bad
  • Most cats don’t care about the smell

The PETARMOR Topical Flea & Tick Treatment is a combination of fipronil (the active ingredient), in a waterbase spray. The PETARMOR Plus Flea & Tick Treatment starts to kill fleas less than 4 hours after application, and ticks within 24 hours. It will also kill flea eggs for up to six weeks.

You apply the spray every month to protect your cat from fleas and ticks and give it a fully waterproof and fast acting formula. It works on both kittens and adult cats.

It does contain a strong smell that is well known for being similar to fishy.

14. TropiClean Natural Flea & Tick Spot on Treatments

Our rating: 7 / 10

TropiClean Natural Flea & Tick Spot on Treatments

Check Price on Amazon

If your cat has fleas or ticks, there’s no reason to panic. Leaving the problem to last for months or putting off treatment a few more days won’t make the situation any simpler. That’s where this product comes in to help.

TropiClean Flea & Tick Spot-On for Cats will provide protection against common external parasites that can bother a cat. The ingredients are all-natural and safer for cats and kittens alike.

Contrary to popular belief, it won’t have any lasting negative impacts on your cat or kitty.

15. Adventure Plus

Our rating: 7 / 10

Adventure Plus

Check Price on Amazon

Pros:

  • This is an effective flea treatment for cats
  • Easy to use
  • Comes in a pack
  • Doesn’t have a bad smell
  • Prevents flea infestation
  • Repels ticks
  • For 4 pounds and above
  • Effect lasts for 4 months

Cons:

  • Price is on the higher side
  • Not a perfect solution
  • Not very difficult to administer
  • Not sure about its long term effectivity

This product from Nutra Pro is said to kill adult fleas within 30 minutes and ticks within 48 hours. This comes in a pack of 4 units with a total of 18 doses.

The drops are said to be perfect for use on cats weighing over 4 pounds. It is also said to repel ticks, which can be dangerous in many ways.

This is a good solution for cat owners who require flea and tick treatment. It is easy to administer and reasonablly priced, but needs to be implemented carefully to get the best effects.

16. FRONTLINE Plus Flea and Tick Treatment

Our rating: 7 / 10

FRONTLINE Plus Flea and Tick Treatment

Check Price on Amazon

Pros:

  • One of the highest recommended flea drops for cats in most online reviews
  • Comes in different sizes – Small Cats > 6lbs, Medium Cats > 6lbs, Large Cats > 15 lbs and Kittens > 8 lbs
  • Can be used on dogs as well (over 24 weeks) in three sizes – Small Dogs > 15 lbs, Medium Dogs 15-45 lbs and Large Dogs > 45 lbs
  • Contains permethrin (0.46%) for treatment of fleas and ticks
  • Available in two different sizes
  • Each tube contains pipettes that allow you to administer 0.030 mL on small cats/kittens (over 8 weeks), Medium cats over 6 lbs, Large cats over 15 lbs and Large Dog > 45 lbs depending on size
  • Also contains imidacloprid for quick kill of fleas on cats
  • Contains 2 pipettes to make sure your cat gets the right dosage
  • Active ingredient is IGR (insect growth regulator) that aids in the prevention of flea eggs from hatching by inhibiting development of larvae and pupae
  • Contains synergized pyrethroid for quick kill of adult fleas on cats

17. Sentry Fiproguard Flea and Tick Topical

Our rating: 7 / 10

Sentry Fiproguard Flea and Tick Topical

Check Price on Amazon

Customer Rating : 4.8 out of 5 stars ( 5 )

Why is This Our Best Pick?

Our experts have tested many cat flea collars available in the market. And, this is hands down the most effective. It’s also our best flea and tick drops for cats. It’s not just us the experts who recommend this. Thousands of cat owners have reviewed the product which is also why it’s so highly rated on Amazon.

18. Sentry Fiproguard Plus

Our rating: 7 / 10

Sentry Fiproguard Plus

Check Price on Amazon

Pros:

  • Affordable product
  • Effective on all life stages of fleas
  • No oily residue left behind
  • Safe for kittens 4 weeks+ and pregnant and nursing
  • Applicator top
  • Veterinary recommended
  • Kills fleas and 100% of ticks within 10 minutes
  • Can be safely reapplied each month
  • Active ingredient: Fipronil 9.8%
  • Also active ingredient: (S)-Methoprene 11.8%

Cons:

  • Does not kill ticks in 7-10 days as Vetdepot claims
  • Is not waterproof

Topical Flea and Tick Control, Protects Cats for 1 Month, Gray.

19. Zodiac Flea & Tick Spot On

Our rating: 7 / 10

Zodiac Flea & Tick Spot On

Check Price on Amazon

Owing to its unique design, Zodiac flea tick spot can get rid of pesky fleas and ticks within 30 minutes of its application. It contains an IGR that interrupts the flea life cycle at different stages.

It also kills fleas that are already on your pet, so they don’t have time to reproduce and make your pet infested again.

Its formula is strong enough to handle a whole month of flea and tick infestations resulting from the sand pit and cat-and-mouse games that cats and their owners play.

20. TevraPet FirstAct Plus Cat Flea and Tick Treatment

Our rating: 7 / 10

TevraPet FirstAct Plus Cat Flea and Tick Treatment

Check Price on Amazon

Pros:

  • The perfect flea treatment for cats weighing over 5 lbs
  • May kill fleas in as little as 12 hours
  • Kills fleas, flea eggs, ticks, and flea larvae
  • Made from natural and safe ingredients
  • Has fewer and milder side effects compared to other medications on the market

Cons:

  • The active ingredient fipronil, which protects against adult fleas, is only available in chickens and other poultry. This could be a problem if you have other pets in your house that your cat could eat
  • It’s advised to keep pets away from areas of heavy infestation for up to 2 weeks after application

8 Count.

Here’s are some things you should know about fleas and why you’re looking for flea treatment for your cat. Flea bites cause cats to scratch and bite themselves, resulting in irritation and inflammation. This can perpetuate flea infestation, which can result to more irritation, infestation, and even anemia. Fleas can also transmit several diseases to your pet.

21. Advantage II Flea Prevention

Our rating: 6 / 10

Advantage II Flea Prevention

Check Price on Amazon

Pros:

  • Long-lasting protection – one monthly dose gives your cat continuous flea protection for up to three months
  • Good for kittens over 8 weeks old
  • Uses the same active ingredients as frontline
  • Kills fleas, flea eggs and larvae, and ticks – as well as protecting your cat from flea re-infestations
  • Fast-acting – immediate results with no side effects
  • Safe and convenient – can be applied once a month
  • Prevents ticks or kills ticks on contact
  • Has a pleasant smell (providing a quick visual check to see if the fleas have been eliminated)
  • Contains a special applicator, which makes the application process easier
  • It’s a lot less expensive than frontline, and the effect is going to be the same

22. Combiva II

Our rating: 6 / 10

Combiva II

Check Price on Amazon

Pros:

  • Safe and effective
  • Ideal for cats weighing 9 lbs and above
  • Available in tablet form for quick and easy administration
  • Works within one hour
  • Available over-the-counter

Cons:

  • Available only for cats (not dogs)
  • Available only for cats weighing 9 lbs and above

If you need a spot on flea and tick medication for your cat, then we’d suggest that you take a look at the Combiva II for cats over 9 lbs from Combiva. It’s specially designed to treat both fleas and ticks, and fast too.

The ticks that this product is effective against include the American dog tick, brown dog tick, and deer tick.

This product is very easy to administer. It’s available in tablet form and you only need to give your cat one tablet per month.

23. Catego Fast-Acting Flea & Tick Treatment

Our rating: 6 / 10

Catego Fast-Acting Flea & Tick Treatment

Check Price on Amazon

Pros:

  • Simple to use, packaged in 2 treat pipettes per blister package to control flea infestation on a single site.
  • Kills flea larvae within 6 hours of application.
  • Stops eggs from hatching and irreparably damages tapeworm larvae the next day.
  • Protects against flea reinfestation for up to 4 weeks.
  • With its ultra-fast action, Catego is an effective weapon for sudden flea infestations.

Cons:

  • Cats must be at least 1.5 lbs and over 8 weeks of age before using the product.
  • It is suitable for both indoor and outdoor use
  • Ideal for cats sensitive to other brands and/or affected by steroid-induced side effects
  • Quickly and effectively combats fleas and flea larvae due to its quick-action formula; the product kills fleas within 6 hours post-administration in both kittens and cats.

For Up To 4 Weeks, Active Ingredients: Imidacloprid 10% and Pyriproxyfen 3%

What Reviewers Say:

It's a great product for my cats, I am really glad I use it. It is least expensive from other brands. It's an old product and I get it from Amazon because I trust this brand.

24. Frontline Gold

Our rating: 5 / 10

Frontline Gold

Check Price on Amazon

Pros:

  • Aerosol mist allows for accurate long distance application, reducing the number of accidental misses.
  • Proprietary odor neutralizer block the unpleasant smell of the Frontline formulation.
  • Long-lasting efficacy through unique combination of active ingredients.
  • Contains an insect growth regulator which breaks the life cycle of fleas by killing flea eggs and larvae before they can emerge as adults, reducing the flea population over successive generations.
  • Dual-action formula that instantly kills adult fleas and provides relief from flea allergy dermatitis caused by the larvae.

Cons:

  • Long-lasting effect requires weekly application for the first month, and then monthly application to maintain flea control.
  • Risk of toxicity may occur after administering to an animal already infested with fleas.
  • Reversible neurological effects may occur at highest doses in pets with a pre-disposition for seizures.
  • Does not kill ticks, so frequent combing with a flea comb is recommended when using this product.

Features:

The 3 in 1 Advantage also includes eggs and larvae control, making it one of the best flea drops for your cat.

Frequently Asked Questions (FAQ)

Which flea drops are best for cats?

The most frequently recommended flea drops are Frontline Plus and Advantage II.

What is the most effective flea and tick treatment for cats?

What's worse than having to deal with an infestation of fleas?

How about having to treat the fleas and ticks on your cat?

A great flea and tick treatment for cats will protect your cat against an infestation as well as treat existing issues.

There are quite a few products to choose from, but we've narrowed it down to a few that we think will make the best choice.

The main benefit to the treatments in this guide is that they are easy to use and designed specifically for your cat. They each have different ingredients and be used on both cats as well as dogs.

What is better for cats Frontline or Advantage?

If you have ever seen the commercial for Advantage, the one where they say 2 out of 3 humans have fleas, there is a good chance that you have an infestation. You don’t have to find little black specks on your pets to know you should do something, the scratching is a good enough indicator that you should treat your cat. I think I would have used Frontline if it were not for the price. It is just expensive. I have used both over the years and both are very effective. The only thing to consider is if your cat is allergic to Frontliner you will need to switch to Advantage.

What is the safest and most effective flea treatment for cats?

Fipronil (Frontline®) is currently the safest and most effective formulation for fleas. Many owners choose first-generation Frontline though, which is both safe and highly effective. Additionally, some colonies have become resistant to it. One advantage to using Frontline® is that it can treat both fleas and ticks. However, an entire colony can become treated with as little as one application.

Some owners choose Advantage® for Cats, and can’t understand why their pet still has fleas. Advantage® contains an insect growth regulator, which disrupts the flea’s life cycle. Unfortunately, a flea still has time to reproduce and bite, thus not eradicating the population. One Advantage® treatment can last about four to six weeks, so it is recommended that you apply it every 30 to 90 days to prevent new infestations.

Conclusion

Whether you have indoor or outdoor cats, you will need to use flea drops to help keep the fleas at bay.

Being the savvy shoppers that we are, we’ve researched and found what we deem are the best flea drops for cats.

In this article, we’ll reveal why we love these products, and what to look out for when making your purchase to ensure you get a quality product that your kitty will tolerate.

Our Recommendation

NameCategoryProduct
Bayer Animal Health Advantage II Flea Prevention and TreatmentBest OverallBayer Animal Health Advantage II Flea Prevention and Treatment
Zodiac Flea & Tick Spot OnBudget PickZodiac Flea & Tick Spot On
Frontline GoldUpgrade PickFrontline Gold